Pediatric-Onset Takayasu Arteritis

Major Criteria

• Angiographic abnormalities (conventional, CT, or magnetic resonance angiography) of the aorta or its main branches

Minor Criteria

• Decreased peripheral artery pulse(s) and/or claudication of extremities
• Blood pressure difference between arms or legs of >10 mm Hg
• Bruits over the aorta and/or its major branches
• Hypertension (defined by childhood normative data)
• Elevated acute-phase reactant (erythrocyte sedimentation rate or C-reactive protein)

Interpretation

• Diagnosis requires the mandatory major (angiographic) criterion plus at least one minor criterion.