Cystic Fibrosis

Diagnostic criteria for cystic fibrosis (clinical/screening plus CFTR dysfunction evidence).

Criteria

Presence of typical clinical features (respiratory, gastrointestinal, or genitourinary) or • A history of CF in a sibling or • A positive newborn screening test
Laboratory evidence for CFTR (CF transmembrane regulator) dysfunction: • Two elevated sweat chloride concentrations obtained on separate days or • Identification of two CF mutations or • An abnormal nasal potential difference measurement

Related guides

Cystic Fibrosis in Children: An A-Z Clinical Monograph

Diagnose paediatric cystic fibrosis — sweat chloride ≥60 mmol/L, CFTR genetics, newborn screening pathway, plus red flags and a multidisciplinary management overview.

Related Respiratory diagnostics

Allergic Rhinitis

Diagnostic approach classifying rhinitis into allergic, occupational, and nonallergic causes.

Asthma

Home management algorithm for asthma exacerbations by peak flow/symptom zone.

Allergic Bronchopulmonary Aspergillosis (ABPA)

Diagnostic criteria for allergic bronchopulmonary aspergillosis, distinguishing central-bronchiectasis and seropositive forms.

Eosinophilic Pneumonia

Diagnostic criteria for idiopathic chronic and idiopathic acute eosinophilic pneumonia.

Hypersensitivity Pneumonitis

Diagnostic findings for hypersensitivity pneumonitis — antigen exposure, clinical/radiographic features, BAL, challenge testing, and histopathology.

Reactive Airway Disease

Diagnostic features of reactive airways dysfunction syndrome following irritant exposure.

Reference this at the bedside, offline — get the Doctaverse app.