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Neonatology

Neonatal Bilirubin Thresholds (AAP 2022)

Phototherapy, escalation, and exchange-transfusion total-serum-bilirubin thresholds for infants ≥35 weeks (AAP 2022).

Scope: BETA — thresholds digitized from the AAP 2022 curves (±~0.3 mg/dL) and hour-interpolated; the 35–37 wk early-hour exchange cells especially should be confirmed against the official AAP 2022 figures / PediTools before acting. Decision also allows a bilirubin:albumin ratio criterion (not modelled here). ≥35 wk only; not for preterm <35 wk.

Inputs

FieldUnitNotes
Gestational age weeks 35–42
Postnatal age hours 0–336
Total serum bilirubin mg/dL 0–50
Neurotoxicity risk factors albumin <3.0, isoimmune/G6PD/other hemolysis, sepsis, or clinical instability in last 24h

FAQ

What is the Neonatal Bilirubin Thresholds (AAP 2022)?

Phototherapy, escalation, and exchange-transfusion total-serum-bilirubin thresholds for infants ≥35 weeks (AAP 2022).

What inputs does the Neonatal Bilirubin Thresholds (AAP 2022) need?

Gestational age (weeks), Postnatal age (hours), Total serum bilirubin (mg/dL), Neurotoxicity risk factors.

Are there any limitations?

BETA — thresholds digitized from the AAP 2022 curves (±~0.3 mg/dL) and hour-interpolated; the 35–37 wk early-hour exchange cells especially should be confirmed against the official AAP 2022 figures / PediTools before acting. Decision also allows a bilirubin:albumin ratio criterion (not modelled here). ≥35 wk only; not for preterm <35 wk.

Related guides

Neonatal Bilirubin Thresholds (AAP 2022): Phototherapy and Exchange by Hour and Gestation

The 2022 AAP hyperbilirubinemia thresholds for infants ≥35 weeks — how gestational age, postnatal hour, and neurotoxicity risk factors move the phototherapy and exchange lines, plus the escalation-of-care zone. BETA digitized curves.

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